做某事有问题，英语中可以用以下几个表达方式来表达：

1. Have difficulty doing something. (做某事有困难)

例如：I'm having difficulty understanding this math problem. (我做这个数学题有困难)

2. Encounter problems doing something. (做某事遇到问题)

例如：I encountered some problems while trying to fix my car. (我修车时遇到了一些问题)

3. Face challenges doing something. (做某事面临挑战)

例如：I'm facing challenges in completing this project on time. (我完成这个项目的时间面临挑战)

4. Run into obstacles doing something. (做某事遇到障碍)

例如：We ran into some obstacles while trying to launch the new product. (我们试图推出新产品时遇到了一些障碍)

5. Encounter difficulties doing something. (做某事遇到困难)

例如：I encountered difficulties in learning a new language. (我学习新语言时遇到了困难)

以上是一些常用的表达方式，希望对大家有所帮助。